Non‐response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS‐3) in patients with chronic hepatitis C, viral genotype 1

BACKGROUND: Interferon α (IFN‐α) activated cellular signalling is negatively regulated by inhibitory factors, including the suppressor of cytokine signalling (SOCS) family. The effects of host factors such as obesity on hepatic expression of these inhibitory factors in subjects with chronic hepatiti...

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Detalhes bibliográficos
Main Authors: Walsh, M J, Jonsson, J R, Richardson, M M, Lipka, G M, Purdie, D M, Clouston, A D, Powell, E E
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Hepatitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856185/
https://ncbi.nlm.nih.gov/pubmed/16299039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.069674
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