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Deletions in Klebsiella pneumoniae R plasmids induced by growth in the presence of acridine orange at high temperature.

The generation in vivo of plasmids deleted at specific sites in strains of Klebsiella pneumoniae containing R plasmids, by treatment with high concentrations of acridine orange (1.2 mg/ml) at 42 degrees C are reported. These deletions seem to be site specific because loss of specific restriction fra...

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Bibliografiske detaljer
Main Authors: Zorzópulos, J, Trevisán, A R, Denoya, C D
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC185611/
https://ncbi.nlm.nih.gov/pubmed/6375565
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