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CRE/CREB-Driven Up-Regulation of Gene Expression by Chronic Social Stress in CRE-Luciferase Transgenic Mice: Reversal by Antidepressant Treatment

BACKGROUND: It has been suggested that stress provokes neuropathological changes and may thus contribute to the precipitation of affective disorders such as depression. Likewise, the pharmacological therapy of depression requires chronic treatment and is thought to induce a positive neuronal adaptat...

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Detalhes bibliográficos
Main Authors: Böer, Ulrike, Alejel, Tahseen, Beimesche, Stephan, Cierny, Irmgard, Krause, Doris, Knepel, Willhart, Flügge, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855984/
https://ncbi.nlm.nih.gov/pubmed/17487276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000431
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