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Enhanced efficacy of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine in combination with beta-interferon against herpes simplex virus type 2 in mice.

The acyclic nucleoside 9-(1,3-dihydroxy-2- propoxymethyl )guanine (DHPG) and natural mouse interferon beta ( MuIFN -beta) were evaluated for their efficacy alone and in combination against herpes simplex virus type 2 systemic infections in mice. Intraperitoneally infected animals were treated once a...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Fraser-Smith, E B, Eppstein, D A, Marsh, Y V, Matthews, T R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1984
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6610387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.5.563
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