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NF-κB inhibition causes spontaneous apoptosis in Epstein–Barr virus-transformed lymphoblastoid cells

Epstein–Barr virus (EBV) transforms B lymphocytes into lymphoblastoid cell lines usurping the Notch and tumor necrosis factor receptor pathways to effect transcription including NF-κB activation. To determine whether NF-κB activity is essential in the growth and survival of EBV-transformed lymphobla...

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Détails bibliographiques
Auteurs principaux: Cahir-McFarland, Ellen D., Davidson, David M., Schauer, Stephanie L., Duong, Jimmy, Kieff, Elliott
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC18557/
https://ncbi.nlm.nih.gov/pubmed/10811897
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