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DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication
Cells that suffer substantial inhibition of DNA replication halt their cell cycle via a checkpoint response mediated by the PI3 kinases ATM and ATR. It is unclear how cells cope with milder replication insults, which are under the threshold for ATM and ATR activation. A third PI3 kinase, DNA-depende...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855631/ https://ncbi.nlm.nih.gov/pubmed/17280685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.018 |
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