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Gene Targeting in Gram-Negative Bacteria by Use of a Mobile Group II Intron (“Targetron”) Expressed from a Broad-Host-Range Vector

Mobile group II introns (“targetrons”) can be programmed for insertion into virtually any desired DNA target with high frequency and specificity. Here, we show that targetrons expressed via an m-toluic acid-inducible promoter from a broad-host-range vector containing an RK2 minireplicon can be used...

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Detalhes bibliográficos
Main Authors: Yao, Jun, Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855620/
https://ncbi.nlm.nih.gov/pubmed/17322321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02829-06
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