Roxithromycin Favorably Modifies the Initial Phase of Resistance against Infection with Macrolide-Resistant Streptococcus pneumoniae in a Murine Pneumonia Model

Sub-MIC levels of macrolides down-regulate bacterial virulence factors and suppress inflammatory processes. The ability of macrolides to reduce the production of pneumolysin has been shown to explain the discrepancy between in vitro resistance and outcomes with macrolides against macrolide-resistant...

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Bibliografiske detaljer
Main Authors: Yasuda, Yasuki, Kasahara, Kei, Mizuno, Fumiko, Nishi, Kazuyuki, Mikasa, Keiichi, Kita, Eiji
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855574/
https://ncbi.nlm.nih.gov/pubmed/17353244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01459-06
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