Roxithromycin Favorably Modifies the Initial Phase of Resistance against Infection with Macrolide-Resistant Streptococcus pneumoniae in a Murine Pneumonia Model

Sub-MIC levels of macrolides down-regulate bacterial virulence factors and suppress inflammatory processes. The ability of macrolides to reduce the production of pneumolysin has been shown to explain the discrepancy between in vitro resistance and outcomes with macrolides against macrolide-resistant...

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Bibliographische Detailangaben
Hauptverfasser: Yasuda, Yasuki, Kasahara, Kei, Mizuno, Fumiko, Nishi, Kazuyuki, Mikasa, Keiichi, Kita, Eiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855574/
https://ncbi.nlm.nih.gov/pubmed/17353244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01459-06
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