EDP-420, a Bicyclolide (Bridged Bicyclic Macrolide), Is Active against Mycobacterium avium

Infection caused by Mycobacterium avium complex (MAC) is common in patients with immunosuppression, such as AIDS, and deficiencies of gamma interferon and interleukin-12, as well as patients with chronic lung diseases. Treatment of MAC disease is limited since few drugs show in vivo activity. We tes...

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Detalhes bibliográficos
Main Authors: Bermudez, Luiz E., Motamedi, Nima, Chee, Christopher, Baimukanova, Gyulnar, Kolonoski, Peter, Inderlied, Clark, Aralar, Priscilla, Wang, Guoqiang, Phan, Ly Tam, Young, Lowell S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855536/
https://ncbi.nlm.nih.gov/pubmed/17296742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01303-06
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