EDP-420, a Bicyclolide (Bridged Bicyclic Macrolide), Is Active against Mycobacterium avium

Infection caused by Mycobacterium avium complex (MAC) is common in patients with immunosuppression, such as AIDS, and deficiencies of gamma interferon and interleukin-12, as well as patients with chronic lung diseases. Treatment of MAC disease is limited since few drugs show in vivo activity. We tes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bermudez, Luiz E., Motamedi, Nima, Chee, Christopher, Baimukanova, Gyulnar, Kolonoski, Peter, Inderlied, Clark, Aralar, Priscilla, Wang, Guoqiang, Phan, Ly Tam, Young, Lowell S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855536/
https://ncbi.nlm.nih.gov/pubmed/17296742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01303-06
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