In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups

PD 0305970 and PD 0326448 are new bacterial gyrase and topoisomerase inhibitors (quinazoline-2,4-diones) that possess outstanding in vitro and in vivo activities against a wide spectrum of bacterial species including quinolone- and multidrug-resistant gram-positive and fastidious organism groups. Th...

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Bibliografische gegevens
Hoofdauteurs: Huband, Michael D., Cohen, Michael A., Zurack, Margaret, Hanna, Debra L., Skerlos, Laura A., Sulavik, Mark C., Gibson, Glenn W., Gage, Jeffrey W., Ellsworth, Edmund, Stier, Michael A., Gracheck, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855495/
https://ncbi.nlm.nih.gov/pubmed/17261623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01321-06
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