In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups

PD 0305970 and PD 0326448 are new bacterial gyrase and topoisomerase inhibitors (quinazoline-2,4-diones) that possess outstanding in vitro and in vivo activities against a wide spectrum of bacterial species including quinolone- and multidrug-resistant gram-positive and fastidious organism groups. Th...

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Detalhes bibliográficos
Main Authors: Huband, Michael D., Cohen, Michael A., Zurack, Margaret, Hanna, Debra L., Skerlos, Laura A., Sulavik, Mark C., Gibson, Glenn W., Gage, Jeffrey W., Ellsworth, Edmund, Stier, Michael A., Gracheck, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855495/
https://ncbi.nlm.nih.gov/pubmed/17261623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01321-06
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