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miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely

MicroRNAs (miRNAs) are a family of ≈22-nt noncoding RNAs that can posttranscriptionally regulate gene expression. Several miRNAs are specifically expressed in hematopoietic cells. Here we show that one such miRNA, miR-150, is mainly expressed in the lymph nodes and spleen and is highly up-regulated...

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Detalhes bibliográficos
Main Authors: Zhou, Beiyan, Wang, Stephanie, Mayr, Christine, Bartel, David P., Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855395/
https://ncbi.nlm.nih.gov/pubmed/17438277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702409104
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