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Role of group-conserved residues in the helical core of β(2)-adrenergic receptor
G protein-coupled receptors (GPCRs) belonging to class A contain several highly conserved (>90%) amino acids in their transmembrane helices. Results of mutational studies of these highly conserved residues suggest a common mechanism for locking GPCRs in an inactive conformation and for their subs...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855394/ https://ncbi.nlm.nih.gov/pubmed/17438264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702024104 |
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