Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans

In the cilia of the nematode Caenorhabditis elegans, anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3 kinesin. These complexes function together in the cilia middle segments, whereas OSM-3 alone mediates transport in the distal segments. Not muc...

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Bibliografiske detaljer
Main Authors: Burghoorn, Jan, Dekkers, Martijn P. J., Rademakers, Suzanne, de Jong, Ton, Willemsen, Rob, Jansen, Gert
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855366/
https://ncbi.nlm.nih.gov/pubmed/17420466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606974104
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