Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans

In the cilia of the nematode Caenorhabditis elegans, anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3 kinesin. These complexes function together in the cilia middle segments, whereas OSM-3 alone mediates transport in the distal segments. Not muc...

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Detalles Bibliográficos
Autores principales: Burghoorn, Jan, Dekkers, Martijn P. J., Rademakers, Suzanne, de Jong, Ton, Willemsen, Rob, Jansen, Gert
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855366/
https://ncbi.nlm.nih.gov/pubmed/17420466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606974104
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