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Multipotent hematopoietic cells susceptible to alternative double-strand break repair pathways that promote genome rearrangements

Chromosomal translocations are a hallmark of hematopoietic malignancies. The initial molecular events or pathways that lead to translocations in hematopoietic cells are largely unknown, particularly in the stem cell-enriched population postulated to be the initial target for these events. We used in...

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Autors principals: Francis, Richard, Richardson, Christine
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855232/
https://ncbi.nlm.nih.gov/pubmed/17473170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1522807
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