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The mouse dead-end gene isoform α is necessary for germ cell and embryonic viability
Inactivation of the dead-end (Dnd1) gene in the Ter mouse strain results in depletion of primordial germ cells (PGCs) so that mice become sterile. However, on the 129 mouse strain background, loss of Dnd1 also increases testicular germ cell tumor incidence in parallel to PGC depletion. We report tha...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855146/ https://ncbi.nlm.nih.gov/pubmed/17291453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.138 |
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