The Ter mutation in the Dead-end gene causes germ cell loss and testicular germ cell tumours

The Ter mutation causes primordial germ cell (PGC) loss on all mouse genetic backgrounds (Fig. 1a) with deficiency of PGCs1 starting at embryonic day 8. Ter is also a potent modifier of spontaneous testicular germ cell tumour (TGCT) susceptibility in the 129 family of inbred strains and increases TG...

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Autors principals: Youngren, Kirsten K., Coveney, Douglas, Peng, Xiaoning, Bhattacharya, Chitralekha, Schmidt, Laura S., Nickerson, Michael L., Lamb, Bruce T., Deng, Jian Min, Behringer, Richard R., Capel, Blanche, Rubin, Edward M., Nadeau, Joseph H., Matin, Angabin
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421521/
https://ncbi.nlm.nih.gov/pubmed/15902260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03595
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