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Brc1-Mediated Rescue of Smc5/6 Deficiency: Requirement for Multiple Nucleases and a Novel Rad18 Function

Smc5/6 is a structural maintenance of chromosomes complex, related to the cohesin and condensin complexes. Recent studies implicate Smc5/6 as being essential for homologous recombination. Each gene is essential, but hypomorphic alleles are defective in the repair of a diverse array of lesions. A par...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lee, Karen M., Nizza, Suzanne, Hayes, Thomas, Bass, Kirstin L., Irmisch, Anja, Murray, Johanne M., O'Connell, Matthew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Copyright © 2007 by the Genetics Society of America 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855136/
https://ncbi.nlm.nih.gov/pubmed/17277362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.067801
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