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Analysis of meiotic recombination in 22q11.2, a region that frequently undergoes deletions and duplications

BACKGROUND: The 22q11.2 deletion syndrome is the most frequent genomic disorder with an estimated frequency of 1/4000 live births. The majority of patients (90%) have the same deletion of 3 Mb (Typically Deleted Region, TDR) that results from aberrant recombination at meiosis between region specific...

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Bibliografiske detaljer
Main Authors: Torres-Juan, Laura, Rosell, Jordi, Sánchez-de-la-Torre, Manuel, Fibla, Joan, Heine-Suñer, Damià
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855045/
https://ncbi.nlm.nih.gov/pubmed/17397557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-14
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