Determination of flumequine and a hydroxy metabolite in biological fluids by high-pressure liquid chromatographic, fluorometric, and microbiological methods.

A sensitive and specific high-pressure liquid chromatographic method is described for the determination of the antibacterial drug flumequine and a major metabolite, 7-hydroxyflumequine, in human plasma and urine. The assay was linear over a concentration range of 1 to 120 micrograms/ml for both comp...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Harrison, L I, Schuppan, D, Rohlfing, S R, Hansen, A R, Hansen, C S, Funk, M L, Collins, S H, Ober, R E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6372680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.3.301
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