Determination of flumequine and a hydroxy metabolite in biological fluids by high-pressure liquid chromatographic, fluorometric, and microbiological methods.

A sensitive and specific high-pressure liquid chromatographic method is described for the determination of the antibacterial drug flumequine and a major metabolite, 7-hydroxyflumequine, in human plasma and urine. The assay was linear over a concentration range of 1 to 120 micrograms/ml for both comp...

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Detalhes bibliográficos
Main Authors: Harrison, L I, Schuppan, D, Rohlfing, S R, Hansen, A R, Hansen, C S, Funk, M L, Collins, S H, Ober, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC185504/
https://ncbi.nlm.nih.gov/pubmed/6372680
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