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Troyer Syndrome Protein Spartin Is Mono-Ubiquitinated and Functions in EGF Receptor Trafficking

Troyer syndrome is an autosomal recessive hereditary spastic paraplegia caused by mutation in the spartin (SPG20) gene, which encodes a widely expressed protein of unknown function. This mutation results in premature protein truncation and thus might signify a loss-of-function disease mechanism. In...

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Detalhes bibliográficos
Main Authors: Bakowska, Joanna C., Jupille, Henri, Fatheddin, Parvin, Puertollano, Rosa, Blackstone, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855030/
https://ncbi.nlm.nih.gov/pubmed/17332501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0833
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