Cholesterol-dependent clustering of IL-2Rα and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts

Immunogold staining and electron microscopy show that IL-2 receptor α-subunits exhibit nonrandom surface distribution on human T lymphoma cells. Analysis of interparticle distances reveals that this clustering on the scale of a few hundred nanometers is independent of the presence of IL-2 and of the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Vereb, G., Matkó, J., Vámosi, G., Ibrahim, S. M., Magyar, E., Varga, S., Szöllősi, J., Jenei, A., Gáspár, R., Waldmann, T. A., Damjanovich, S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.11.6013
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