Cholesterol-dependent clustering of IL-2Rα and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts

Immunogold staining and electron microscopy show that IL-2 receptor α-subunits exhibit nonrandom surface distribution on human T lymphoma cells. Analysis of interparticle distances reveals that this clustering on the scale of a few hundred nanometers is independent of the presence of IL-2 and of the...

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Detalhes bibliográficos
Main Authors: Vereb, G., Matkó, J., Vámosi, G., Ibrahim, S. M., Magyar, E., Varga, S., Szöllősi, J., Jenei, A., Gáspár, R., Waldmann, T. A., Damjanovich, S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18550/
https://ncbi.nlm.nih.gov/pubmed/10823948
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