Murine Cerebral Malaria Development Is Independent of Toll-Like Receptor Signaling

Malaria pigment hemozoin was reported to activate the innate immunity by Toll-like receptor (TLR)-9 engagement. However, the role of TLR activation for the development of cerebral malaria (CM), a lethal complication of malaria infection in humans, is unknown. Using Plasmodium berghei ANKA (PbA) infe...

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Detalhes bibliográficos
Main Authors: Togbe, Dieudonnée, Schofield, Louis, Grau, Georges E., Schnyder, Bruno, Boissay, Victorine, Charron, Sabine, Rose, Stéphanie, Beutler, Bruce, Quesniaux, Valérie F.J., Ryffel, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854958/
https://ncbi.nlm.nih.gov/pubmed/17456769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060889
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