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IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization

Cytokines play an important role in modulating inflammatory responses and, as a result, airway tone. IL-10 is a regulatory cytokine that has been suggested for treatment of asthma because of its immunosuppressive and anti-inflammatory properties. In contrast to these suggestions, we demonstrate in a...

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Bibliografische gegevens
Hoofdauteurs: Mäkelä, M. J., Kanehiro, A., Borish, L., Dakhama, A., Loader, J., Joetham, A., Xing, Z., Jordana, M., Larsen, G. L., Gelfand, E. W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18549/
https://ncbi.nlm.nih.gov/pubmed/10811896
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