A phage integrase directs efficient site-specific integration in human cells
The integrase from the Streptomyces phage φC31 carries out efficient recombination between the attP site in the phage genome and the attB site in the host bacterial chromosome. In this paper, we show that the enzyme also functions in human cells. A plasmid assay system was constructed that measured...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10801973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090527097 |
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