Phenothiazine compounds inhibit in vitro growth of pathogenic free-living amoebae.

The phenothiazine compounds trifluoperazine dihydrochloride and chlorpromazine hydrochloride have in vitro activity against the pathogenic free-living amoebae Naegleria fowleri, Acanthamoeba culbertsoni, and Acanthamoeba polyphaga. Drug concentrations of 10 microM were amoebastatic; concentrations o...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Schuster, F L, Mandel, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6703673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.109
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