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Phenothiazine compounds inhibit in vitro growth of pathogenic free-living amoebae.

The phenothiazine compounds trifluoperazine dihydrochloride and chlorpromazine hydrochloride have in vitro activity against the pathogenic free-living amoebae Naegleria fowleri, Acanthamoeba culbertsoni, and Acanthamoeba polyphaga. Drug concentrations of 10 microM were amoebastatic; concentrations o...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Schuster, F L, Mandel, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1984
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6703673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.109
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