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Pharmacology of Cefuroxime as the 1-acetoxyethyl ester in volunteers.

Cefuroxime axetil is a new orally absorbed prodrug of the antibiotic cefuroxime. The results of pharmacological studies in 52 healthy volunteers are presented. Intact cefuroxime axetil was not detected in the systemic circulation, indicating that deesterification to yield cefuroxime occurs rapidly a...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Harding, S M, Williams, P E, Ayrton, J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6703686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.78
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