Pharmacology of Cefuroxime as the 1-acetoxyethyl ester in volunteers.

Cefuroxime axetil is a new orally absorbed prodrug of the antibiotic cefuroxime. The results of pharmacological studies in 52 healthy volunteers are presented. Intact cefuroxime axetil was not detected in the systemic circulation, indicating that deesterification to yield cefuroxime occurs rapidly a...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Harding, S M, Williams, P E, Ayrton, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6703686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.1.78
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