The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture.

1. Some possible molecular mechanisms of action of the anxiolytic, anticonvulsant and neuroprotective agent MK-801 have been examined in 'whole-cell' voltage clamp recordings performed on rat hippocampal and cortical neurones, bovine adrenomedullary chromaffin cells and N1E-115 neuroblasto...

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Autores principales: Halliwell, R. F., Peters, J. A., Lambert, J. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854359/
https://ncbi.nlm.nih.gov/pubmed/2647206
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