Establishment of a murine cell line resistant to arabinosyladenine and devoid of adenosine deaminase activity.
A population of cells stably resistant to a concentration of arabinosyladenine 100-fold greater than that tolerated by wild-type cells was selected over a period of 15 months. The cells are not cross resistant to arabinosylcytosine and may have at least one kinase with altered substrate specificity.
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1983
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185413/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6660862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.6.947 |
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