Establishment of a murine cell line resistant to arabinosyladenine and devoid of adenosine deaminase activity.

A population of cells stably resistant to a concentration of arabinosyladenine 100-fold greater than that tolerated by wild-type cells was selected over a period of 15 months. The cells are not cross resistant to arabinosylcytosine and may have at least one kinase with altered substrate specificity.

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Shipman, C, Tong, S L, Smith, S H, Katlama, N B, Drach, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185413/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6660862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.6.947
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