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Functional and direct binding studies using subtype selective muscarinic receptor antagonists.
1. Muscarinic receptor antagonists were examined in direct binding studies on guinea-pig cardiac and cortical muscarinic receptors. Pirenzepine, dicyclomine and hexahydroadiphenine were shown to be selective ligands for the putative M1-muscarinic receptor. 2. Functional affinity estimates of the mus...
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Principais autores: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1988
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853838/ https://ncbi.nlm.nih.gov/pubmed/2897216 |
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