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Functional and direct binding studies using subtype selective muscarinic receptor antagonists.

1. Muscarinic receptor antagonists were examined in direct binding studies on guinea-pig cardiac and cortical muscarinic receptors. Pirenzepine, dicyclomine and hexahydroadiphenine were shown to be selective ligands for the putative M1-muscarinic receptor. 2. Functional affinity estimates of the mus...

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Hlavní autoři: Kunysz, E. L., Michel, A. D., Whiting, R. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853838/
https://ncbi.nlm.nih.gov/pubmed/2897216
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