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Rapid Simultaneous Amplification and Detection of the MBR/JH Chromosomal Translocation by Fluorescence Melting Curve Analysis

Polymerase chain reaction (PCR) amplification and product analysis for the detection of chromosomal translocations, such as the t(14;18), has traditionally been a two-step process. PCR product detection has generally entailed gel electrophoresis and/or hybridization or sequencing for confirmation of...

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Autori principali: Bohling, Sandra D., King, Thomas C., Wittwer, Carl T., Elenitoba-Johnson, Kojo S. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853425/
https://ncbi.nlm.nih.gov/pubmed/9916923
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