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In Situ Visualization of Intratumor Growth Factor Signaling : Immunohistochemical Localization of Activated ERK/MAP Kinase in Glial Neoplasms

Abnormal growth factor signaling is implicated in the pathogenesis of gliomas. The extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway is a likely target, linking receptor tyrosine kinase activation to downstream serine/threonine phosphorylation events regulat...

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Bibliografiske detaljer
Main Authors: Mandell, James W., Hussaini, Isa M., Zecevic, Maja, Weber, Michael J., VandenBerg, Scott R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853399/
https://ncbi.nlm.nih.gov/pubmed/9811332
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