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Exploiting the Yeast L-A Viral Capsid for the In Vivo Assembly of Chimeric VLPs as Platform in Vaccine Development and Foreign Protein Expression

A novel expression system based on engineered variants of the yeast (Saccharomyces cerevisiae) dsRNA virus L-A was developed allowing the in vivo assembly of chimeric virus-like particles (VLPs) as a unique platform for a wide range of applications. We show that polypeptides fused to the viral capsi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Powilleit, Frank, Breinig, Tanja, Schmitt, Manfred J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853235/
https://ncbi.nlm.nih.gov/pubmed/17476337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000415
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