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Acidic Residues on the Voltage-Sensor Domain Determine the Activation of the NaChBac Sodium Channel

The voltage-sensing domain of voltage-gated ion channels is characterized by specific, conserved, charged residues. Positively charged residues on segment S4 are the main contributors to voltage-sensing and negatively charged residues on the S2 and S3 segments are believed to participate to the proc...

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Bibliografiske detaljer
Main Authors: Blanchet, Jonathan, Pilote, Sylvie, Chahine, Mohamed
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853154/
https://ncbi.nlm.nih.gov/pubmed/17325004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090464
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