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Population Stratification of a Common APOBEC Gene Deletion Polymorphism

The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a detailed sequence and population genetic analysis of a 29.5-kb common human deletion polymorphism that remo...

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Bibliografiske detaljer
Main Authors: Kidd, Jeffrey M, Newman, Tera L, Tuzun, Eray, Kaul, Rajinder, Eichler, Evan E
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853121/
https://ncbi.nlm.nih.gov/pubmed/17447845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030063
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