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Loss of p16/INK4A Protein Expression in Non-Hodgkin’s Lymphomas Is a Frequent Finding Associated with Tumor Progression

The CDKN2A gene located on chromosome region 9p21 encodes the cyclin-dependent kinase-4 inhibitor p16/INK4A, a negative cell cycle regulator. We analyzed p16/INK4A expression in different types of non-Hodgkin’s lymphoma to determine whether the absence of this protein is involved in lymphomagenesis,...

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Detalhes bibliográficos
Main Authors: Villuendas, Raquel, Sánchez-Beato, Margarita, Martínez, Juan C., Saez, Ana I., Martinez-Delgado, Beatriz, García, Juan F., Mateo, M. Sol, Sanchez-Verde, L., Benítez, Javier, Martínez, Pedro, Piris, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853011/
https://ncbi.nlm.nih.gov/pubmed/9736037
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