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Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation.

Apo E, a key regulator of cholesterol-rich lipoprotein metabolism, is synthesized by numerous extrahepatic tissues. Although its synthesis in macrophages is documented, the contribution of macrophage-derived apo E to hepatic clearance of serum cholesterol is unknown. To address this issue bone marro...

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Autors principals: Boisvert, W A, Spangenberg, J, Curtiss, L K
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC185301/
https://ncbi.nlm.nih.gov/pubmed/7635947
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