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Cloning and characterization of the mammalian brain-specific, Mg(2+)-dependent neutral sphingomyelinase

The enzymatic breakdown of sphingomyelin by sphingomyelinases is considered the major source of the second messenger ceramide. Studies on the contribution of the various described acidic and neutral sphingomyelinases to the signaling pool of ceramide have been hampered by the lack of molecular data...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hofmann, Kay, Tomiuk, Stefan, Wolff, Gabriela, Stoffel, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.11.5895
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