Macrophages in Human Atheroma Contain PPARγ : Differentiation-Dependent Peroxisomal Proliferator-Activated Receptor γ (PPARγ) Expression and Reduction of MMP-9 Activity through PPARγ Activation in Mononuclear Phagocytes in Vitro

Mononuclear phagocytes play an important role in atherosclerosis and its sequela plaque rupture in part by their secretion of matrix metalloproteinases (MMPs), including MMP-9. Peroxisomal proliferator-activated receptor γ (PPARγ), a transcription factor in the nuclear receptor superfamily, regulate...

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Main Authors: Marx, Nikolaus, Sukhova, Galina, Murphy, Curran, Libby, Peter, Plutzky, Jorge
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 1998
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852950/
https://ncbi.nlm.nih.gov/pubmed/9665460
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