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Macrophages in Human Atheroma Contain PPARγ : Differentiation-Dependent Peroxisomal Proliferator-Activated Receptor γ (PPARγ) Expression and Reduction of MMP-9 Activity through PPARγ Activation in Mononuclear Phagocytes in Vitro

Mononuclear phagocytes play an important role in atherosclerosis and its sequela plaque rupture in part by their secretion of matrix metalloproteinases (MMPs), including MMP-9. Peroxisomal proliferator-activated receptor γ (PPARγ), a transcription factor in the nuclear receptor superfamily, regulate...

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Autors principals: Marx, Nikolaus, Sukhova, Galina, Murphy, Curran, Libby, Peter, Plutzky, Jorge
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852950/
https://ncbi.nlm.nih.gov/pubmed/9665460
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