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Human genetics of infectious diseases: a unified theory

Since the early 1950s, the dominant paradigm in the human genetics of infectious diseases postulates that rare monogenic immunodeficiencies confer vulnerability to multiple infectious diseases (one gene, multiple infections), whereas common infections are associated with the polygenic inheritance of...

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Autors principals: Casanova, Jean-Laurent, Abel, Laurent
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852849/
https://ncbi.nlm.nih.gov/pubmed/17255931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601558
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