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Human genetics of infectious diseases: a unified theory

Since the early 1950s, the dominant paradigm in the human genetics of infectious diseases postulates that rare monogenic immunodeficiencies confer vulnerability to multiple infectious diseases (one gene, multiple infections), whereas common infections are associated with the polygenic inheritance of...

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Detalhes bibliográficos
Main Authors: Casanova, Jean-Laurent, Abel, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852849/
https://ncbi.nlm.nih.gov/pubmed/17255931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601558
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