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Treatment of marrow stroma with interferon-alpha restores normal beta 1 integrin-dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors. Role of MIP-1 alpha.

The mechanisms by which interferon-alpha (IFN-alpha) restores normal hematopoiesis in chronic myelogenous leukemia (CML) are not well understood. We have recently demonstrated that IFN-alpha acts directly on CML hematopoietic progenitors to restore their adhesion to marrow stroma by modulating beta...

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Pubblicato in:J Clin Invest
Autori principali: Bhatia, R, McGlave, P B, Verfaillie, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7543495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118141
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