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A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses

DNA damage causes genome instability and cell death, but many of the cellular responses to DNA damage still remain elusive. We here report a human protein, PALF (PNK and APTX-like FHA protein), with an FHA (forkhead-associated) domain and novel zinc-finger-like CYR (cysteine–tyrosine–arginine) motif...

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Detalhes bibliográficos
Main Authors: Kanno, Shin-ichiro, Kuzuoka, Hiroyuki, Sasao, Shigeru, Hong, Zehui, Lan, Li, Nakajima, Satoshi, Yasui, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852789/
https://ncbi.nlm.nih.gov/pubmed/17396150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601663
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