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Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. However, whether granzymes use additional mechanisms to exert their antipathogen activity remains elusive....

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Autori principali: Andrade, Felipe, Fellows, Edward, Jenne, Dieter E, Rosen, Antony, Young, C S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852776/
https://ncbi.nlm.nih.gov/pubmed/17363894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601650
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